Kerstin Heurling Selected Research

flutemetamol

11/2019	Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
3/2019	Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies.
10/2018	Estimation of amyloid distribution by [18F]flutemetamol PET predicts the neuropathological phase of amyloid β-protein deposition.
4/2017	Brain uptake and safety of Flutemetamol F 18 injection in Japanese subjects with probable Alzheimer's disease, subjects with amnestic mild cognitive impairment and healthy volunteers.
12/2016	Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection.
2/2016	Imaging β-amyloid using [(18)F]flutemetamol positron emission tomography: from dosimetry to clinical diagnosis.
11/2015	Parametric imaging and quantitative analysis of the PET amyloid ligand [(18)F]flutemetamol.
8/2015	[(18)F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of amyloid-β pathology.
6/2015	An exploratory efficacy study of the amyloid imaging agent [(18)F]flutemetamol in Japanese Subjects.
4/2014	Diagnostic effectiveness of quantitative [¹⁸F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus.

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Kerstin Heurling Research Topics

Disease

14	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 04/2014
5	Dementia (Dementias) 01/2020 - 09/2014
5	Amyloid Plaque 11/2019 - 11/2015
4	Insulin Resistance 01/2020 - 01/2018
3	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2021 - 12/2016
3	Type 2 Diabetes Mellitus (MODY) 01/2021 - 08/2018
3	Death (Near-Death Experience) 10/2018 - 08/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2017 - 02/2016
3	Cognitive Dysfunction 04/2017 - 04/2014
1	Heart Failure 01/2021
1	Cerebral Small Vessel Diseases 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Pituitary Neoplasms (Pituitary Adenoma) 01/2020
1	Neoplasms (Cancer) 01/2020
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2020
1	Non-alcoholic Fatty Liver Disease 12/2019
1	Fatty Liver 12/2019
1	Hyperlipidemias (Hyperlipidemia) 12/2019
1	Hyperphagia (Overeating) 12/2019
1	Weight Gain 12/2019
1	Overweight 12/2019
1	Proteostasis Deficiencies 01/2019
1	Mental Disorders (Mental Disorder) 01/2019
1	Hyperinsulinism (Hyperinsulinemia) 08/2018
1	Prediabetic State (Prediabetes) 08/2018
1	Parkinson Disease (Parkinson's Disease) 09/2017
1	Atrophy 12/2016
1	Anxiety Disorders (Anxiety Disorder) 10/2016
1	Social Phobia 10/2016
1	Normal Pressure Hydrocephalus 04/2014

Drug/Important Bio-Agent (IBA)

13	Amyloid (Amyloid Fibrils)IBA 01/2021 - 04/2014
10	flutemetamolIBA 11/2019 - 04/2014
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 08/2018
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2018
2	Peptides (Polypeptides)IBA 01/2020 - 11/2019
2	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 01/2020 - 03/2019
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2018
1	SodiumIBA 01/2021
1	dapagliflozinIBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	Edotreotide (SMT 487)IBA 01/2020
1	Somatostatin Receptors (Somatostatin Receptor)IBA 01/2020
1	CeramidesIBA 12/2019
1	EnzymesIBA 12/2019
1	Fatty Acids (Saturated Fatty Acids)IBA 12/2019
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2019
1	LipidsIBA 12/2019
1	Insulin (Novolin)FDA Link 01/2018
1	FluorineIBA 01/2018
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2018
1	Drug Receptors (Drug Receptor)IBA 09/2017
1	Serotonin (5 Hydroxytryptamine)IBA 10/2016
1	Tryptophan HydroxylaseIBA 10/2016
1	Carboxy-LyasesIBA 10/2016
1	Tryptophan (L-Tryptophan)FDA Link 10/2016
1	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 02/2016

Therapy/Procedure

1	Therapeutics 02/2016